Andrea Malandrino
Andrea Malandrino
Visiting Researcher
Room: Room 02.074
Room: Room 02.074
- Phone number: +49 9131 85-25606
- Email: andrea.malandrino1@upc.edu
Andrea’s research interests include tissue and cell biomechanics and mechanobiology, especially focusing on the dynamics of extracellular matrices. Recent works have included vascularized microphysiological 3D platforms (e.g. using microfluidics) for modeling disease aspects, and for investigating biomechanical aspects and patterning in organogenesis. His research combines both experimental “wet” and computational/theoretical “dry” approaches.
2021
2021
- Derivation and characterisation of endothelial cells from patients with chronic thromboembolic pulmonary hypertension
In Sci Rep, volume 11, number 1, pp. 18797, 2021. - Poroelastic osmoregulation of living cell volume
In iScience, volume 24, number 12, pp. 103482, 2021.
2019
2019
- Dynamic filopodial forces induce accumulation, damage, and plastic remodeling of 3D extracellular matrices
In PLoS Comput Biol, volume 15, number 4, pp. e1006684, 2019.
2018
2018
- Complex mechanics of the heterogeneous extracellular matrix in cancer
In Extreme Mech Lett, volume 21, pp. 25-34, 2018. - In Vitro Modeling of Mechanics in Cancer Metastasis
In ACS Biomater Sci Eng, volume 4, number 2, pp. 294-301, 2018. - Cell contraction induces long-ranged stress stiffening in the extracellular matrix
In Proc Natl Acad Sci U S A, volume 115, number 16, pp. 4075-4080, 2018.
2016
2016
- Patient-specific fracture risk assessment of vertebrae: A multiscale approach coupling X-ray physics and continuum micromechanics
In Int J Numer Method Biomed Eng, volume 32, number 9, 2016.
2015
2015
- On the relative relevance of subject-specific geometries and degeneration-specific mechanical properties for the study of cell death in human intervertebral disk models
In Front Bioeng Biotechnol, volume 3, pp. 5, 2015. - Models and Experiments in Bioengineering: Why Synergies Are Encouraged
In Front Bioeng Biotechnol, volume 3, pp. 207, 2015.
2014
2014
- Numerical exploration of the combined effect of nutrient supply, tissue condition and deformation in the intervertebral disc
In J Biomech, volume 47, number 6, pp. 1520-5, 2014. - The role of endplate poromechanical properties on the nutrient availability in the intervertebral disc
In Osteoarthritis Cartilage, volume 22, number 7, pp. 1053-60, 2014.
2013
2013
- Regional annulus fibre orientations used as a tool for the calibration of lumbar intervertebral disc finite element models
In Comput Methods Biomech Biomed Engin, volume 16, number 9, pp. 923-8, 2013.
2011
2011
- Comparison of four methods to simulate swelling in poroelastic finite element models of intervertebral discs
In J Mech Behav Biomed Mater, volume 4, number 7, pp. 1234-41, 2011. - The effect of sustained compression on oxygen metabolic transport in the intervertebral disc decreases with degenerative changes
In PLoS Comput Biol, volume 7, number 8, pp. e1002112, 2011.
2009
2009
- Statistical factorial analysis on the poroelastic material properties sensitivity of the lumbar intervertebral disc under compression, flexion and axial rotation
In J Biomech, volume 42, number 16, pp. 2780-8, 2009.
2008
2008
- An accurate estimation of bone density improves the accuracy of subject-specific finite element models
In J Biomech, volume 41, number 11, pp. 2483-91, 2008.
2007
2007
- Subject-specific finite element models can accurately predict strain levels in long bones
In J Biomech, volume 40, number 13, pp. 2982-9, 2007.

