The insertion of a bronchoscope into a ventilated airway can profoundly alter respiratory mechanics, yet its effects on ventilation are difficult to anticipate in clinical practice. This study introduces a quantitative framework to better understand and manage these challenges in mechanically ventilated patients. By combining bench measurements, lung simulation, and a novel scaling law based on effective tube diameter, the study enables accurate prediction of resistance-related ventilation impairments across ventilator modes. The findings challenge long-standing size-based recommendations and demonstrate that pressure-controlled ventilation with automatic tube compensation can fully prevent these impairments. This work provides clinically relevant tools to support safer bronchoscopy and more informed airway management in the intensive care setting.
Read the full publication in Intensive Care Medicine Experimental: https://rdcu.be/eU6zF