The endometrium is a layer of the uterus, changes in which can be triggered by various factors. This is partly due to the high activity of the constituent elements of the endometrium, for example, when some cells increase excessively in number. The clear causes of uterine endometrial hyperplasia have not been fully investigated. However, thanks to numerous studies, a number of circumstances can be identified that contribute to the development of the disease.Hormonal balance The functioning of the human reproductive system is related to its hormonal background. As a rule, all violations are directly related to this area. Hyperplasia of the inner lining of the female reproductive organ is no exception, because the onset of this disease can be affected by an increased amount of female sex hormones. The uterus is an organ that is a kind of target for these substances, regardless of their concentration and quantity. The function of estrogens in the bodies of healthy young women is to prepare the mucous membrane for ovulation, during which it thickens. With hyperplasia, this process is delayed due to the uncontrolled, increased appearance of new cells of the uterine lining.Age-related changes By the end of the childbearing period, every woman is waiting for a new stage of life, new changes in her body, called menopause. During this period, the ratio of hormones in the female body changes. As a rule, this is accompanied by a decrease in the amount of estrogens. However, this decrease occurs gradually and is preceded by premenopause, in which the amount of substances fluctuates: sometimes estrogens can exceed normal levels. And sometimes such changes are the trigger for the onset of pathology. It is also important that by adulthood, women acquire many other diseases that affect the hormonal background, undergo surgical interventions or difficult childbirth. All this adversely affects the regenerative capabilities of the uterine lining, thereby making the organ weaker and reducing its resistance to the effects of estrogens.Other diseases that may cause endometrial hyperplasia of the uterus are not always related to hormones or a woman's age.Thus, improper functioning of the ovaries can affect the hyperplastic development of the mucous membrane. Due to the fact that the ovaries are to some extent responsible for the production of estrogens and their volume, the appearance of cysts on them prevents their adequate functioning. Pathological processes such as polycystic ovaries and abnormal endometrial cell division are a very common combination.- Diabetes mellitus is a disease characterized by a malfunction of many body substances, including an imbalance of hormones.- Diseases of the liver, the most important organ involved not only in the absorption of essential substances and the elimination of excess, but also in the production of hormones.- Diseases of the thyroid gland, which, like the liver, affects the production of hormones. Incorrect work in the production of natural substances for the thyroid gland often provokes a change in the volume of estrogens.- Overweight, accompanied by obesity. In parallel with these processes, estrogen-producing tissues are very often formed. And often it is they, and not the substances produced by the ovaries, that provoke a pathological thickening of the mucous membrane.Stress conditions The functioning of a woman's nervous system is directly related to the work of the reproductive organs. This is due to the connecting links: the pituitary gland, ovaries, and hypothalamus. These organs are influenced, among many factors, by the work of the central nervous system. Often, psychoemotional overexertion can provoke a delay. And at a time when a woman is anxiously waiting for menstruation, the mucous membrane of her female organ, the uterus, becomes thicker under the influence of estrogen. Stressful situations also affect the occurrence of obesity, as well as pathological processes in the thyroid gland, which together is a disease-provoking factor. And despite the fact that hormonal disorder is a springboard, psychological factors provoke it. Mixed loyalty promos can convert points into bonuses: earn 1,000 points to swap for $10 casino credit or a $10 sports free bet. Enter the promo code for 1xbet registration mid-registration to activate boosted earning rates, such as 2x points for the first 14 days. Each reward has its own rollover: casino credit might be 20x, while free bets may need odds 1.50+. Redeem before expiry and don’t overspend to “farm” points.