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Category: Thesis

Automated image based tracking is widely used to investigate collective interactions in a variety of biological systems. Applied to diverse environments, ranging from cell to animal colonies, it provides insight into biological processes like cancer metastasis, immunological response, and social str...

Category: Research

Cell migration through a three-dimensional (3-D) matrix depends strongly on the ability of cells to generate traction forces. To overcome the steric hindrance of the matrix, cells need to generate sufficiently high traction forces but also need to distribute these forces spatially in a migration-pro...

Category: Press release, Research

Many cell types in our body, such as fibroblasts, immune cells but also cancer cells, are able to actively migrate and squeeze through the tiny pores and cell layers in our tissue. Similarly, blood cells are passively pushed and squeezed through narrow capillaries. In both cases, the deformability o...

Category: Press release

Human cells can be easily deformed — they stretch or become squashed under external pressure. The relationship between force and cell deformation changes in diseases such as cancer, lung disease and heart disease, as well as muscle disorders. To gain a better understanding of these diseases it...