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Bachelor/Master Projects

Wolfgang Goldmann

 

Prof. Dr. Wolfgang Goldmann

Professor Goldmann’s research focuses on the protein and cell biomechanics. Specifically, it deals with the binding of membrane-bound proteins to the actin cytoskeleton and focal adhesion points as the well as with their influence on the visco/elastic/plastic behavior in cells, using biochemical and biophysical methods. In addition, Professor Goldmann is studying the function of focal adhesion proteins on cellular traction, motility, and chemical signaling in 2D and 3D environments.

Professor Wolfgang H. Goldmann, PhD is a German/American citizen. He studied Medicine at Ludwig-Maximilian University in Munich and later Physical Biochemistry at the University of Bristol, England, where he received his PhD in 1990. He then moved back to Munich to take up a position under the direction of Professor Erich Sackmann at the Biophysics Department of the Technical University. From 1995 to 2004 he worked at Harvard Medical School in Boston under the auspices of Professor Amin Arnaout and Professor Don Ingber. He was a lecturer in Physical Cell Biology and Biochemistry until he left. In 2004, he spent his sabbatical as a visiting Professor at the Center for Medical Physics and Technology, Friedrich-Alexander University in Erlangen, and he is now a W2-Professor.

2018
[127] M. Chatzifrangkeskou, D. Yadin, T. Marais, S. Chardonnet, M. Cohen-Tannoudji, N. Mougenot, A. Schmitt, S. Crasto, E. Di Pasquale, C. Macquart, Y. Tanguy, I. Jebeniani, M. Puceat, B. Morales Rodriguez, W. H. Goldmann, M. Dal Ferro, M. G. Biferi, P. Knaus, G. Bonne, H. J. Worman, A. Muchir
Cofilin-1 phosphorylation catalyzed by ERK1/2 alters cardiac actin dynamics in dilated cardiomyopathy caused by lamin A/C gene mutation
In Hum Mol Genet, volume 27, 2018. [bibtex] [pdf] [doi]
[126] W. H. Goldmann
Intermediate filaments and cellular mechanics
In Cell Biol Int, volume 42, 2018. [bibtex] [pdf] [doi]
[125] W. H. Goldmann
Molecular interactions between vinculin and phospholipids
In Cell Biol Int, volume 42, 2018. [bibtex] [pdf] [doi]
[124] N. Mucke, L. Kammerer, S. Winheim, R. Kirmse, J. Krieger, M. Mildenberger, J. Bassler, E. Hurt, W. H. Goldmann, U. Aebi, K. Toth, J. Langowski, H. Herrmann
Assembly Kinetics of Vimentin Tetramers to Unit-Length Filaments: A Stopped-Flow Study
In Biophys J, volume 114, 2018. [bibtex] [pdf] [doi]
[123] FE Ciraldo, L Liverani, L Gritsch, WH Goldmann, AR Boccaccini
Synthesis and Characterization of Silver-Doped Mesoporous Bioactive Glass and Its Applications in Conjunction with Electrospinning
In Materials (Basel, Switzerland), volume 11, 2018. [bibtex] [pdf] [doi]
[122] L. Gritsch, C. Lovell, W. H. Goldmann, A. R. Boccaccini
Do bioresorbable polyesters have antimicrobial properties?
In J Mater Sci Mater Med, volume 29, 2018. [bibtex] [pdf] [doi]
[121] L. Gritsch, C. Lovell, W. H. Goldmann, A. R. Boccaccini
Fabrication and characterization of copper(II)-chitosan complexes as antibiotic-free antibacterial biomaterial
In Carbohydr Polym, volume 179, 2018. [bibtex] [pdf] [doi]
2017
[120] N. S. Radda'a, W. H. Goldmann, R. Detsch, J. A. Roether, L. Cordero-Arias, S. Virtanen, T. Moskalewicz, A. R. Boccaccini
Electrophoretic deposition of tetracycline hydrochloride loaded halloysite nanotubes chitosan/bioactive glass composite coatings for orthopedic implants
In Surface & Coatings Technology, volume 327, 2017. [bibtex] [doi]
[119] M. A. Ur Rehman, S. Ferraris, W. H. Goldmann, S. Perero, F. E. Bastan, Q. Nawaz, G. G. D. Confiengo, M. Ferraris, A. R. Boccaccini
Antibacterial and Bioactive Coatings Based on Radio Frequency Co-Sputtering of Silver Nanocluster-Silica Coatings on PEEK/Bioactive Glass Layers Obtained by Electrophoretic Deposition
In ACS Appl Mater Interfaces, volume 9, 2017. [bibtex] [doi]
[118] Y. Yang, K. Zheng, R. Liang, A. Mainka, N. Taccardi, J. A. Roether, R. Detsch, W. H. Goldmann, S. Virtanen, A. R. Boccaccini
Cu-releasing bioactive glass/polycaprolactone coating on Mg with antibacterial and anticorrosive properties for bone tissue engineering
In Biomed Mater, volume 13, 2017. [bibtex] [pdf] [doi]
[117] S. Diermeier, J. Iberl, K. Vetter, M. Haug, C. Pollmann, B. Reischl, A. Buttgereit, S. Schurmann, M. Sporrer, W. H. Goldmann, B. Fabry, F. Elhamine, R. Stehle, G. Pfitzer, L. Winter, C. S. Clemen, H. Herrmann, R. Schroder, O. Friedrich
Early signs of architectural and biomechanical failure in isolated myofibers and immortalized myoblasts from desmin-mutant knock-in mice
In Sci Rep, volume 7, 2017. [bibtex] [pdf] [doi]
[116] J. Branis, C. Pataki, M. Sporrer, R. C. Gerum, A. Mainka, V. Cermak, W. H. Goldmann, B. Fabry, J. Brabek, D. Rosel
The role of focal adhesion anchoring domains of CAS in mechanotransduction
In Sci Rep, volume 7, 2017. [bibtex] [pdf] [doi]
2016
[115] N. Bonakdar, A. Schilling, R. Gerum, J. L. Alonso, W. H. Goldmann
Innovations in Measuring Cellular Mechanics
Chapter in (Kazuo Tanishita, Kimiko Yamamoto, eds.), Springer Japan, 2016. [bibtex] [pdf] [doi]
[114] Y. Ge, Y. H. Lin, L. A. Lautscham, W. H. Goldmann, B. Fabry, C. A. Naumann
N-cadherin-functionalized polymer-tethered multi-bilayer: a cell surface-mimicking substrate to probe cellular mechanosensitivity
In Soft Matter, volume 12, 2016. [bibtex] [pdf] [doi]
[113] S. Schurmann, S. Wagner, S. Herlitze, C. Fischer, S. Gumbrecht, A. Wirth-Hucking, G. Prolss, L. A. Lautscham, B. Fabry, W. H. Goldmann, V. Nikolova-Krstevski, B. Martinac, O. Friedrich
The IsoStretcher: An isotropic cell stretch device to study mechanical biosensor pathways in living cells
In Biosens Bioelectron, volume 81, 2016. [bibtex] [pdf] [doi]
2015
[112] S. Osmanagic-Myers, S. Rus, M. Wolfram, D. Brunner, W. H. Goldmann, N. Bonakdar, I. Fischer, S. Reipert, A. Zuzuarregui, G. Walko, G. Wiche
Plectin reinforces vascular integrity by mediating crosstalk between the vimentin and the actin networks
In J Cell Sci, volume 128, 2015. [bibtex] [pdf] [doi]
[111] V. Auernheimer, L. A. Lautscham, M. Leidenberger, O. Friedrich, B. Kappes, B. Fabry, W. H. Goldmann
Vinculin phosphorylation at residues Y100 and Y1065 is required for cellular force transmission
In J Cell Sci, volume 128, 2015. [bibtex] [pdf] [doi]
[110] F.M. Hecht, J. Rheinlaender, N. Schierbaum, W. H. Goldmann, B. Fabry, T.E. Schäffer
Imaging viscoelastic properties of living cells by AFM: Power-law rheology on the nanoscale
In Soft Matter, volume 11, 2015. [bibtex] [pdf]
[109] L. Winter, W. H. Goldmann
Biomechanical characterization of myofibrillar myopathies
In Cell Biol Int, volume 39, 2015. [bibtex] [pdf] [doi]
[108] N. Bonakdar, A. Schilling, M. Sporrer, P. Lennert, A. Mainka, L. Winter, G. Walko, G. Wiche, B. Fabry, W. H. Goldmann
Determining the mechanical properties of plectin in mouse myoblasts and keratinocytes
In Exp Cell Res, 2015. [bibtex] [pdf] [doi]
2014
[107] V. Auernheimer, W. H. Goldmann
Vinculin E29R mutation changes cellular mechanics
In Biochem Biophys Res Commun, volume 452, 2014. [bibtex] [pdf] [doi]
[106] N. Bonakdar, A. Schilling, P. Lennert, M. Sporrer, R. C. Gerum, J. L. Alonso, W. H. Goldmann
Measuring mechanical properties in cells: three easy methods for biologists
In Cell Biol Int, 2014. [bibtex] [pdf] [doi]
[105] W. H. Goldmann
Mechanosensation: A Basis Cellular Process
volume 126, 2014. [bibtex] [pdf]
[104] V. Auernheimer, W. H. Goldmann
Serine phosphorylation on position 1033 of vinculin impacts cellular mechanics
In Biochem Biophys Res Commun, 2014. [bibtex] [pdf] [doi]
[103] L. A. Lautscham, C. Y. Lin, V. Auernheimer, C. A. Naumann, W. H. Goldmann, B. Fabry
Biomembrane-mimicking lipid bilayer system as a mechanically tunable cell substrate
In Biomaterials, volume 35, 2014. [bibtex] [pdf] [doi]
[102] L. Winter, I. Staszewska, E. Mihailovska, I. Fischer, W. H. Goldmann, R. Schroder, G. Wiche
Chemical chaperone ameliorates pathological protein aggregation in plectin-deficient muscle
In J Clin Invest, 2014. [bibtex] [pdf] [doi]
[101] W. H. Goldmann
Vinculin-p130Cas interaction is critical for focal adhesion dynamics and mechano-transduction
In Cell Biol Int, 2014. [bibtex] [pdf] [doi]
[100] R. Janostiak, J. Brabek, V. Auernheimer, Z. Tatarova, L. A. Lautscham, T. Dey, J. Gemperle, R. Merkel, W. H. Goldmann, B. Fabry, D. Rosel
CAS directly interacts with vinculin to control mechanosensing and focal adhesion dynamics
In Cell Mol Life Sci, volume 71, 2014. [bibtex] [pdf] [doi]
2013
[99] L. Lautscham, C. Yu-Hung Lin, V. Auernheimer, D. Minner, W. H. Goldmann, C. A. Naumann, B. Fabry
Mechanosensing of Cells in Laminin-Fuctionalized Biomembrane-Mimicking Substrates
In Biophysical Journal, volume 104, 2013. [bibtex] [pdf] [doi]
[98] J. Lange, V. Auernheimer, P. L. Strissel, W. H. Goldmann
Influence of focal adhesion kinase on the mechanical behavior of cell populations
In Biochem Biophys Res Commun, 2013. [bibtex] [pdf] [doi]
[97] W. H. Goldmann, V. Auernheimer, I. Thievessen, B. Fabry
Vinculin, cell mechanics, and tumor cell invasion
In Cell Biol Int, 2013. [bibtex] [pdf]
2012
[96] W. H. Goldmann
Mechanotransduction and Focal Adhesions
In Cell Biol Int, 2012. [bibtex] [pdf]
[95] W. H. Goldmann
Mechanotransduction in cells
In Cell Biol. Int., volume 36, 2012. [bibtex] [pdf]
[94] J. L. Alonso, W. H. Goldmann
Influence of divalent cations on the cytoskeletal dynamics of K562 cells determined by nano-scale bead tracking
In Biochem Biophys Res Commun, volume 421, 2012. [bibtex] [pdf]
[93] N Bonakdar, Luczak J., L. Lautscham, M. Czonstke, T.M. Koch, A. Mainka, T. Jungbauer, W.H. Goldmann, R. Schröder, B. Fabry
Biomechanical characterization of a desminopathy in primary human myoblasts
In Biochem Biophys Res Commun, volume 419, 2012. [bibtex] [pdf] [doi]
2011
[92] T. Dey, M. C. Mann, W. H. Goldmann
Comparing mechano-transduction in fibroblasts deficient of focal adhesion proteins
In Biochem Biophys Res Commun, volume 413, 2011. [bibtex] [pdf]
[91] B. Fabry, A. Klemm, S. Kienle, T.E. Schäffer, W. H. Goldmann
Focal Adhesion Kinase Stabilizes the Cytoskeleton
In Biophys J, volume 101, 2011. [bibtex] [pdf]
[90] G. Diez, V. Auernheimer, B. Fabry, W. H. Goldmann
Head/tail interaction of vinculin influences cell mechanical behavior
In Biochem Biophys Res Commun, volume 406, 2011. [bibtex] [pdf]
[89] A. Eekhoff, N. Bonakdar, J. L. Alonso, B. Hoffmann, W. H. Goldmann
Glomerular podocytes: A study of mechanical properties and mechano-chemical signaling
In Biochem Biophys Res Commun, volume 406, 2011. [bibtex] [pdf]
2010
[88] K. Küpper, N. Lang, C. Mohl, N. Kirchgessner, S. Born, W. H. Goldmann, R. Merkel, B. Hoffmann
Tyrosine Phosphorylation of Vinculin at Position 1065 modifies Focal Adhesion Dynamics and Cell Tractions
In Biochem Biophys Res Commun, volume 399, 2010. [bibtex] [pdf]
[87] V. F. Wirth, F. List, G. Diez, W. H. Goldmann
Vinculin's C-terminal region facilitates phospholipid membrane insertion
In Biochem Biophys Res Commun, volume 398, 2010. [bibtex] [pdf]
[86] W. H. Goldmann
Correlation between the interaction of the vinculin tail domain with lipid membranes, its phosphorylation and cell mechanical behaviour
In Cell Biol Int, volume 34, 2010. [bibtex] [pdf]
[85] A. H. Klemm, S. Kienle, J. Rheinlaender, T. E. Schaffer, W. H. Goldmann
The influence of Pyk2 on the mechanical properties in fibroblasts
In Biochem Biophys Res Commun, volume 393, 2010. [bibtex] [pdf]
[84] V. C. Primo, S. Marusic, C. C. Franklin, W. H. Goldmann, C. G. Achaval, R. N. Smith, M. A. Arnaout, B. Nikolic
Anti-PR3 immune responses induce segmental and necrotizing glomerulonephritis
In Clin Exp Immunol, volume 159, 2010. [bibtex] [pdf]
[83] C. T. Mierke, P. Kollmannsberger, D. P. Zitterbart, G. Diez, T. M. Koch, S. Marg, W. H. Ziegler, W. H. Goldmann, B. Fabry
Vinculin facilitates cell invasion into three-dimensional collagen matrices
In J Biol Chem, volume 285, 2010. [bibtex] [pdf]
2009
[82] G. Diez, P. Kollmannsberger, C. T. Mierke, T. M Koch, H. Vali, B. Fabry, W. H. Goldmann
Anchorage of vinculin to lipid membranes influences cell mechanical properties
In Biophys J, volume 97, 2009. [bibtex] [pdf]
[81] K. B. Kegel, V. Schewkunov, E. Sapp, N. Masso, E. E. Wanker, M. DiFiglia, W. H. Goldmann
Polyglutamine Expansion in Huntingtin Increases Insertion into Lipid Bilayers
In Biochem Biophys Res Commun, volume 387, 2009. [bibtex] [pdf]
[80] C. Möhl, N. Kirchgessner, C. Schafer, K. Kupper, S. Born, G. Diez, W. H. Goldmann, R. Merkel, B. Hoffmann
Becoming stable and strong: The interplay between vinculin exchange dynamics and adhesion strength during adhesion site maturation
In Cell Motil Cytoskeleton, volume 66, 2009. [bibtex] [pdf]
[79] P. Zhang, Y. Luo, B. Chasan, S. Gonzalez-Perrett, N. Montalbetti, G. A. Timpanaro, M. D. Cantero, A. J. Ramos, W. H. Goldmann, J. Zhou, H. F. Cantiello
The Multimeric Structure of Polycystin-2 (TRPP2): Structural-Functional Correlates of Homo- and Hetero-multimers with TRPC1
In Hum Mol Genet, 2009. [bibtex] [pdf]
[78] A. H. Klemm, G. Diez, J. L. Alonso, W. H. Goldmann
Comparing the mechanical influence of vinculin, focal adhesion kinase and p53 in mouse embryonic fibroblasts
In Biochem Biophys Res Commun, volume 379, 2009. [bibtex] [pdf]
[77] C. Scholtysek, A. A. Krukiewicz, J. L. Alonso, K. P. Sharma, P. C. Sharma, W. H. Goldmann
Characterizing components of the Saw Palmetto Berry Extract (SPBE) on prostate cancer cell growth and traction
In Biochem Biophys Res Commun, volume 379, 2009. [bibtex] [pdf]
2008
[76] C. T. Mierke, P. Kollmannsberger, D. Paranhos-Zitterbart, J. Smith, B. Fabry, W. H. Goldmann
Mechano-coupling and regulation of contractility by the vinculin tail domain.
In Biophys J, volume 94, 2008. [bibtex] [pdf]
[75] G. Diez, F. List, J. Smith, W. H. Ziegler, W. H. Goldmann
Direct evidence of vinculin tail–lipid membrane interaction in beta-sheet conformation
In Biochem Biophys Res Commun, volume 373, 2008. [bibtex] [pdf]
[74] W. H. Goldmann
Actin: A molecular wire, an electrical cable?
In Cell Biol Int, 2008. [bibtex] [pdf]
[73] V. Schewkunow, K. P. Sharma, G. Diez, A. H. Klemm, P. C. Sharma, W. H. Goldmann
Thermodynamic evidence of non-muscle myosin II-lipid-membrane interaction
In Biochem Biophys Res Commun, volume 366, 2008. [bibtex] [pdf]
2007
[72] W. H. Goldmann, B. Bechinger, T. P. Lele
Cytoskeletal proteins at the lipid membrane
Chapter in (Tien H. T., Ottova-Leitmannova A., eds.), Elsevier, volume 6, 2007. [bibtex] [pdf]
2006
[71] J. Smith, G. Diez, A. H. Klemm, V. Schewkunow, W. H. Goldmann
CapZ-lipid membrane interactions: a computer analysis
In Theor Biol Med Model, volume 3, 2006. [bibtex] [pdf]
[70] A. H. Klemm, K. Sucholdolski, W. H. Goldmann
Mechano-Chemical Signaling in F9 cells
In Cell Biol Int, volume 30, 2006. [bibtex] [pdf]
[69] D. L. Scott, G. Diez, W. H. Goldmann
Protein-lipid interactions: correlation of a predictive algorithm for lipid-binding sites with three-dimensional structural data
In Theor Biol Med Model, volume 3, 2006. [bibtex] [pdf]
2005
[68] K. B. Kegel, E. Sapp, J. Yoder, B. Cuiffo, L. Sobin, Y. J. Kim, Z. H. Qin, M. R. Hayden, N. Aronin, D. L. Scott, G. Isenberg, W. H. Goldmann, M. DiFiglia
Huntingtin associates with acidic phospholipids at the plasma membrane
In J Biol Chem, volume 280, 2005. [bibtex] [pdf]
[67] H. F. Cantiello, N. Montalbetti, W. H. Goldmann, M. K. Raychowdhury, S. Gonzalez-Perrett, G. A. Timpanaro, B. Chasan
Cation channel activity of mucolipin-1: the effect of calcium
In Pflugers Arch, volume 451, 2005. [bibtex] [pdf]
[66] W. H. Goldmann, H. F. Cantiello, B. Chasan
Actomyosin II interaction modulates cell cortex stability
In Cell Biol Int, volume 29, 2005. [bibtex] [pdf]
2004
[65] M. K. Raychowdhury, S. Gonzalez-Perrett, N. Montalbetti, G. A. Timpanaro, B. Chasan, W. H. Goldmann, S. Stahl, A. Cooney, E. Goldin, H. F. Cantiello
Molecular pathophysiology of mucolipidosis type IV: pH dysregulation of the mucolipin-1 cation channel
In Hum Mol Genet, volume 13, 2004. [bibtex] [pdf]
[64] C. Pal Sharma, W. H. Goldmann
Phosphorylation of actin-binding protein (ABP-280; filamin) by tyrosine kinase p56lck modulates actin filament cross-linking
In Cell Biol Int, volume 28, 2004. [bibtex] [pdf]
[63] W. H. Goldmann, G. Isenberg
Signal transmission forces at the cell membrane under debate
In Cell Biol Int, volume 28, 2004. [bibtex] [pdf]
[62] K. Ajroud, T. Sugimori, W. H. Goldmann, D. M. Fathallah, J. P. Xiong, M. A. Arnaout
Binding Affinity of Metal Ions to the CD11b A-domain Is Regulated by Integrin Activation and Ligands
In J Biol Chem, volume 279, 2004. [bibtex] [pdf]
2003
[61] J. L. Alonso, W. H. Goldmann
Feeling the forces: atomic force microscopy in cell biology
In Life Sci, volume 72, 2003. [bibtex] [pdf]
2002
[60] W. H. Goldmann
Examination of actin polymerization and viscosity induced by cations and ionic strength when cross-linked by alpha-actinin
In Cell Biol Int, volume 26, 2002. [bibtex] [pdf]
[59] W. H. Goldmann
p56(lck) Controls phosphorylation of filamin (ABP-280) and regulates focal adhesion kinase (pp125(FAK))
In Cell Biol Int, volume 26, 2002. [bibtex] [pdf]
[58] W. H. Goldmann, G. Isenberg
Actin-related protein (Arp2) inserts into artificial lipid membranes
In Cell Biol Int, volume 26, 2002. [bibtex] [pdf]
[57] W. H. Goldmann
Mechanical aspects of cell shape regulation and signaling
In Cell Biol Int, volume 26, 2002. [bibtex] [pdf]
[56] G. Isenberg, S. Doerhoefer, D. Hoekstra, W. H. Goldmann
Membrane fusion induced by the major lipid-binding domain of the cytoskeletal protein talin
In Biochem Biophys Res Commun, volume 295, 2002. [bibtex] [pdf]
[55] B. Chasan, N. A. Geisse, K. Pedatella, D. G. Wooster, M. Teintze, M. D. Carattino, W. H. Goldmann, H. F. Cantiello
Evidence for direct interaction between actin and the cystic fibrosis transmembrane conductance regulator
In Eur Biophys J, volume 30, 2002. [bibtex] [pdf]
[54] W. H. Goldmann, D. E. Ingber
Intact vinculin protein is required for control of cell shape, cell mechanics, and rac-dependent lamellipodia formation
In Biochem Biophys Res Commun, volume 290, 2002. [bibtex] [pdf]
[53] W. H. Goldmann
The coupling of vinculin to the cytoskeleton is not essential for mechano-chemical signaling in F9 cells
In Cell Biol Int, volume 26, 2002. [bibtex] [pdf]
2001
[52] W. H. Goldmann
Phosphorylation of filamin (ABP-280) regulates the binding to the lipid membrane, integrin, and actin
In Cell Biol Int, volume 25, 2001. [bibtex] [pdf]
[51] W. H. Goldmann, A. L. Sharma, S. J. Currier, P. D. Johnston, A. Rana, C. P. Sharma
Saw palmetto berry extract inhibits cell growth and Cox-2 expression in prostatic cancer cells
In Cell Biol Int, volume 25, 2001. [bibtex] [pdf]
2000
[50] W. H. Goldmann
Binding of tropomyosin-troponin to actin increases filament bending stiffness
In Biochem Biophys Res Commun, volume 276, 2000. [bibtex] [pdf]
[49] W. H. Goldmann
Mechanical manipulation of animal cells: cell indentation
In Biotechnology Letters, volume 22, 2000. [bibtex] [pdf]
[48] F. J. Alenghat, B. Fabry, K. Y. Tsai, W. H. Goldmann, D. E. Ingber
Analysis of cell mechanics in single vinculin-deficient cells using a magnetic tweezer
In Biochem Biophys Res Commun, volume 277, 2000. [bibtex] [pdf]
[47] W. H. Goldmann
Kinetic determination of focal adhesion protein formation
In Biochem Biophys Res Commun, volume 271, 2000. [bibtex] [pdf]
[46] W. H. Goldmann, J.L. Alonso
Cell shape control and mechanical signaling through the cytoskeleton
Chapter in , 2000. [bibtex]
1999
[45] W. H. Goldmann, J. L. Niles, M. A. Arnaout
Interaction of purified human proteinase 3 (PR3) with reconstituted lipid bilayers
In Eur J Biochem, volume 261, 1999. [bibtex] [pdf]
[44] W. H. Goldmann, J. M. Teodoridis, C. P. Sharma, B. Hu, G. Isenberg
Fragments from actin binding protein (ABP-280; filamin) insert into reconstituted lipid layers
In Biochem Biophys Res Commun, volume 259, 1999. [bibtex] [pdf]
[43] W. H. Goldmann, J. M. Teodoridis, C. P. Sharma, J. L. Alonso, G. Isenberg
Fragments from alpha-actinin insert into reconstituted lipid bilayers
In Biochem Biophys Res Commun, volume 264, 1999. [bibtex] [pdf]
[42] W. H. Goldmann, D. Hess, G. Isenberg
The effect of intact talin and talin tail fragment on actin filament dynamics and structure depends on pH and ionic strength
In Eur J Biochem, volume 260, 1999. [bibtex] [pdf]
1998
[41] W. H. Goldmann, Z. Guttenberg
Examination of temperature-induced 'gel-sol' transformation of alpha-actinin/cross-linked actin networks by static light scattering
In FEBS Lett, volume 426, 1998. [bibtex] [pdf]
[40] W. H. Goldmann, Z. Guttenberg, J. X. Tang, K. Kroy, G. Isenberg, R. M. Ezzell
Analysis of the F-actin binding fragments of vinculin using stopped-flow and dynamic light-scattering measurements
In Eur J Biochem, volume 254, 1998. [bibtex] [pdf]
[39] W. H. Goldmann, R. Galneder, M. Ludwig, A. Kromm, R. M. Ezzell
Differences in F9 and 5.51 cell elasticity determined by cell poking and atomic force microscopy
In FEBS Lett, volume 424, 1998. [bibtex] [pdf]
[38] G. Isenberg, W. H. Goldmann
Peptide-specific antibodies localize the major lipid binding sites of talin dimers to oppositely arranged N-terminal 47 kDa subdomains
In FEBS Lett, volume 426, 1998. [bibtex] [pdf]
[37] W. H. Goldmann, R. Galneder, M. Ludwig, W. Xu, E. D. Adamson, N. Wang, R. M. Ezzell
Differences in elasticity of vinculin-deficient F9 cells measured by magnetometry and atomic force microscopy
In Exp Cell Res, volume 239, 1998. [bibtex] [pdf]
[36] W. H. Goldmann, Z. Guttenberg, R.M. Ezzell, G. Isenberg
Study of fast reactions by the stopped flow method
Chapter in , 1998. [bibtex]
1997
[35] W. H. Goldmann, M. Tempel, I. Sprenger, G. Isenberg, R. M. Ezzell
Viscoelasticity of actin-gelsolin networks in the presence of filamin
In Eur J Biochem, volume 246, 1997. [bibtex] [pdf]
[34] W. H. Goldmann, Z. Guttenberg, S. Kaufmann, D. Hess, R. M. Ezzell, G. Isenberg
Examining F-actin interaction with intact talin and talin head and tail fragment using static and dynamic light scattering
In Eur J Biochem, volume 250, 1997. [bibtex] [pdf]
[33] R. M. Ezzell, W. H. Goldmann, N. Wang, N. Parasharama, D. E. Ingber
Vinculin promotes cell spreading by mechanically coupling integrins to the cytoskeleton
In Exp Cell Res, volume 231, 1997. [bibtex] [pdf]
1996
[32] G. Isenberg, V. Niggli, U. Pieper, S. Kaufmann, W. H. Goldmann
Probing phosphatidylinositolphosphates and adenosinenucleotides on talin nucleated actin polymerization
In FEBS Lett, volume 397, 1996. [bibtex] [pdf]
[31] W. H. Goldmann, R. M. Ezzell, E. D. Adamson, V. Niggli, G. Isenberg
Vinculin, talin and focal adhesions
In J Muscle Res Cell Motil, volume 17, 1996. [bibtex] [pdf]
[30] W. H. Goldmann, R. M. Ezzell
Viscoelasticity in wild-type and vinculin-deficient (5.51) mouse F9 embryonic carcinoma cells examined by atomic force microscopy and rheology
In Exp Cell Res, volume 226, 1996. [bibtex] [pdf]
1995
[29] M. Tempel, W. H. Goldmann, G. Isenberg, E. Sackmann
Interaction of the 47-kDa talin fragment and the 32-kDa vinculin fragment with acidic phospholipids: a computer analysis
In Biophys J, volume 69, 1995. [bibtex] [pdf]
[28] R. Götter, W. H. Goldmann, G. Isenberg
Internal actin filament dynamics in the presence of vinculin: a dynamic light scattering study
In FEBS Lett, volume 359, 1995. [bibtex] [pdf]
[27] W. H. Goldmann, R. Senger, S. Kaufmann, G. Isenberg
Determination of the affinity of talin and vinculin to charged lipid vesicles: a light scatter study
In FEBS Lett, volume 368, 1995. [bibtex] [pdf]
[26] R. Senger, W. H. Goldmann, G. Isenberg
The influence of cations on the polymerization of actin and actin in the presence of alpha-actinin/filamin
In Biochem Soc Trans, volume 23, 1995. [bibtex] [pdf]
[25] W. H. Goldmann, M. Schindl, T. J. Cardozo, R. M. Ezzell
Motility of vinculin-deficient F9 embryonic carcinoma cells analyzed by video, laser confocal, and reflection interference contrast microscopy
In Exp Cell Res, volume 221, 1995. [bibtex] [pdf]
[24] G. Isenberg, W. H. Goldmann
Acting-binding proteins - lipid interactions
Chapter in , volume Vol 1, JAI Press Inc., Greenwich, CT, USA, 1995. [bibtex]
[23] R. Senger, W. H. Goldmann
The influence of cations and ionic strength on actin polymerization in the presence/absence of alpha-actinin
In Biochem Mol Biol Int, volume 35, 1995. [bibtex] [pdf]
1994
[22] V. Niggli, S. Kaufmann, W. H. Goldmann, T. Weber, G. Isenberg
Identification of functional domains in the cytoskeletal protein talin
In Eur J Biochem, volume 224, 1994. [bibtex] [pdf]
[21] W. H. Goldmann, A. Bremer, M. Haner, U. Aebi, G. Isenberg
Native talin is a dumbbell-shaped homodimer when it interacts with actin
In J Struct Biol, volume 112, 1994. [bibtex] [pdf]
[20] M. Tempel, W. H. Goldmann, C. Dietrich, V. Niggli, T. Weber, E. Sackmann, G. Isenberg
Insertion of filamin into lipid membranes examined by calorimetry, the film balance technique, and lipid photolabeling
In Biochemistry, volume 33, 1994. [bibtex] [pdf]
[19] W. H. Goldmann, R. Senger, G. Isenberg
Analysis of filamin-actin binding and cross-linking/bundling by kinetic method
In Biochem Biophys Res Commun, volume 203, 1994. [bibtex] [pdf]
[18] M. Tempel, W. H. Goldmann, G. Isenberg
Computer analyses suggest interactions of non-muscle filamin with lipid membranes
In FEBS Lett, volume 350, 1994. [bibtex] [pdf]
1993
[17] W. H. Goldmann, J. Kas, G. Isenberg
Talin decreases the bending elasticity of actin filaments
In Biochem Soc Trans, volume 22, 1993. [bibtex] [pdf]
[16] C. Dietrich, W. H. Goldmann, E. Sackmann, G. Isenberg
Interaction of NBD-talin with lipid monolayers. A film balance study
In FEBS Lett, volume 324, 1993. [bibtex] [pdf]
[15] R. Ruddies, W. H. Goldmann, G. Isenberg, E. Sackmann
The viscoelasticity of entangled actin networks: the influence of defects and modulation by talin and vinculin
In Eur Biophys J, volume 22, 1993. [bibtex] [pdf]
[14] W. H. Goldmann, G. Isenberg
Analysis of filamin and alpha-actinin binding to actin by the stopped flow method
In FEBS Lett, volume 336, 1993. [bibtex] [pdf]
[13] W. H. Goldmann, J. Kas, E. Sackmann, G. Isenberg
Direct visualization of lipid vesicle changes on addition of filamin
In Biochem Soc Trans, volume 21, 1993. [bibtex] [pdf]
1992
[12] S. Kaufmann, J. Kas, W. H. Goldmann, E. Sackmann, G. Isenberg
Talin anchors and nucleates actin filaments at lipid membranes. A direct demonstration
In FEBS Lett, volume 314, 1992. [bibtex] [pdf]
[11] G. Isenberg, W. H. Goldmann
Actin-membrane coupling: a role for talin
In J Muscle Res Cell Motil, volume 13, 1992. [bibtex] [pdf]
[10] W. H. Goldmann, V. Niggli, S. Kaufmann, G. Isenberg
Probing actin and liposome interaction of talin and talin-vinculin complexes: a kinetic, thermodynamic and lipid labeling study
In Biochemistry, volume 31, 1992. [bibtex] [pdf]
[9] W. H. Goldmann, G. Isenberg
Temperature dependent specific heat capacity (Cp) of G-actin and talin or talin-vinculin bound to G-actin
In Biochem Soc Trans, volume 20, 1992. [bibtex] [pdf]
[8] W. H. Goldmann
Talin-lipid interaction
In Biochem Soc Trans, volume 20, 1992. [bibtex] [pdf]
[7] W. H. Goldmann
Thermodynamics of filamin-actin interaction
In Biochem Soc Trans, volume 20, 1992. [bibtex] [pdf]
[6] R. Ruddies, W. H. Goldmann, G. Isenberg, E. Sackmann
The viscoelastic moduli of actin/filamin solutions: a micro-rheologic study
In Biochem Soc Trans, volume 21, 1992. [bibtex] [pdf]
1991
[5] W. H. Goldmann, S. Kaufmann, G. Isenberg
Thermodynamics of talin and talin-vinculin binding to G-actin
In Biochem Soc Trans, volume 20, 1991. [bibtex] [pdf]
[4] W. H. Goldmann, G. Isenberg
Kinetic determination of talin-actin binding
In Biochem Biophys Res Commun, volume 178, 1991. [bibtex] [pdf]
[3] S. Kaufmann, T. Piekenbrock, W. H. Goldmann, M. Barmann, G. Isenberg
Talin binds to actin and promotes filament nucleation
In FEBS Lett, volume 284, 1991. [bibtex] [pdf]
[2] W. H. Goldmann, M. A. Geeves
A "slow" temperature jump apparatus built from a stopped-flow machine
In Anal Biochem, volume 192, 1991. [bibtex] [pdf]
1990
[1] M. A. Geeves, W. H. Goldmann
The influence of anions, ionic strength and organic solvents on the interaction between actin and myosin subfragment 1
In Biochem Soc Trans, volume 18, 1990. [bibtex] [pdf]